The ICREAs

ICREA research professors form a vibrant community of scientists and researchers in all areas of knowledge that contribute to the advancement of humankind by exploring, interpreting and questioning. Have a look and learn about their amazing discoveries and findings here:

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    del Portillo Obando, Hernando A.
    Research Professor at
    Institut de Salut Global Barcelona (ISGlobal)
    Life & Medical Sciences
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    Research interests

    My main research area is the biology of Plasmodium vivax, a neglected human malaria parasite responsible for millions of yearly clinical cases. We are presently looking for mechanistic insights of the role of reticulocyte-derived exosomes, nanovesicles of endocytic origin, in signalling the spleen and the bone marrow to unveil molecular basis of anaemia and splenomegaly.  To pursue bone marrow and spleen studies,  we are implementing the usage of humanized mouse models and organs-on-chip. To use this information in novel control strategies, we are exploring the use of reticulocyte-derived exosomes as a novel vaccine against P. vivax as well as novel biomarkers of liver hypnozite asymptomatic infections. To this end, we are immortalizing cell lines and constructig POC microfluidic devices. Last, to rapidly move this field to translation, we are pursuing the development of exosome-based vaccines against infectious diseases of veterinary importance.

    Key words

    Malaria, Plasmodium vivax, exosomes, vaccine development, biomarkers, molecular insights pathology, lab chip

    ORCID

    : 0000-0002-5278-3452
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    Di Croce, Luciano
    Research Professor at
    Centre de Regulació Genòmica (CRG)
    Life & Medical Sciences
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    Research interests

    Epigenetic changes, such as histone modifications and DNA methylation, are common alterations in cancer cells. Our laboratory is addressing the molecular basis of epigenetic alterations during the early phase of the tumorigenesis process. The expression of onco-proteins in hematopoietic precursor cells provides a unique model system to follow the molecular step from a normal to a transformed cell on the level of gene transcription, nuclear structure and chromatin. More recently, Di Croce lab is interested in understanding how variations in the assembly of the Polycomb complexes occur and influence mES cell differentiation and animal development.  

    Key words

    Cancer, Epigenetics, Gene regulation

    ORCID

    : http://orcid.org/0000-0003-3488-6228

    RESEARCHER ID

    : E-7759-2015
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    Díaz-Andreu García, A. Margarita
    Research Professor at
    Universitat de Barcelona (UB)
    Humanities
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    Research interests

    The three main research areas in which Díaz-Andreu has been active and has led research groups in the last few years are still in place: prehistoric art with an emphasis on archaeoacoustics (ERC Artsoundscapes project, Palarq project), the history of archaeology (interarqweb.wordpress.com) and heritage (gapp.cat and upcoming EU-JPI CURBATHERI project). Her work in archaeoacoustics is highly innovative and she leads an interdisciplinary group of archaeologists, acoustic engineers, ethnomusicologists and psychologists. For this project, in addition to working in the Western Mediterranean area, in 2019 she has undertaken fieldwork Altai (Siberia). In the history of archaeology the high point has been the completion of a manuscript on the history of archaeological tourism to be published by Springer. She will soon be leading the Spanish team of a project on heritage conservation. In all these areas she is leading groups of academics and students (GAPP, InterArq, Artsoundscapes).

    Key words

    History of Archaeology, Prehistoric Art, Rock Art, Prehistory, Identity, Archaeoacoustics, Archaeological Heritage

    ORCID

    : 0000-0003-1043-2336

    RESEARCHER ID

    : B-6146-2014
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    Doblas Reyes, Francisco Javier
    Research Professor at
    Barcelona Supercomputing Center - Centro Nacional de Supercomputación (BSC-CNS)
    Experimental Sciences & Mathematics
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    Research interests

    Global climate is highly variable, which implies that there is much more to understand than just climate change. Climate prediction aims at predicting the variations of climate at different time scales, ranging from one month to several years beyond the start of the forecast. I use an Earth system model based on differential equations to explore the limits of the forecast quality over different parts of the globe, in particular over Africa, South America, the Arctic and Southern Europe. I develop this model to explore the advantages of increasing its resolution to better reproduce the physical processes at the origin of climate variability. I also use statistical techniques to adapt the resulting climate information to specific user needs. Improving the application of this climate information to different socio-economic sectors, with a special focus on energy and disaster risk management, is one of my main targets to try to make a change in both society and the economy.

    Key words

    climate variability, climate prediction, downscaling, climate applications

    ORCID

    : 0000-0002-6622-4280
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    Domingo Sanz, Inés
    Research Professor at
    Universitat de Barcelona (UB)
    Humanities
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    Research interests

    My current research projects aim at brigding the gap between scientific and heritage approaches to one of Europe's most extraordinary bodies of rock art, awarded UNESCO Wolrd Heritage Status in 1998: Levantine rock art. This research has been recently awarded an ERC CoG (2018). Her primary aim is to achieve an holistic view of this art by combining a multidisciplinary (Archaeology, Heritage Science, IT and Ethnoarchaeology) and a multiscale approach (from microanalysis to landscape perspectives) to: a. Redefine LRA through new dating techniques and analythical methods to understand the creative process. b. Use this rock art tradition as a proxy to raise new questions of global interest on the evolution of creative thinking and human cognition. c. Define best practices and protocols for open air rock art conservation and management.

    Key words

    Postpalaeolithic Rock art in Mediterranean Spain (Levantine, Macro-schematic and Schematic traditions), style, techniques, social identity, pigment analysis, ethnoarchaeology, Australian Indigenous rock art, Digital rock art recording methods.

    ORCID

    : orcid/org/0000-0003-4707-8094
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    Durante, Ruben
    Research Professor at
    Universitat Pompeu Fabra (UPF)
    Social & Behavioural Sciences
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    Research interests

    My fields of research are political economy, media economics, and economic development. My research focuses primarily on the functioning and impact of traditional and new media in both mature and consolidating democracies. Specifically, I examine various aspects of the multi-faceted relationship between media, voters, policy-makers and special interests, with particular regard to the ability of an independent press to keep both policy-makers and private interests accountable. Some of the questions tackled in my work include: i) the impact of entertainment television on viewers' socio-political preferences, ii) the strategies used by policy-makers to minimize public scrutiny of their actions, iii) the impact of the Internet on political participation, iv) the influence of corporate interests on the policy-making process, v) the determinants of beliefs about fairness and preferences for redistribution, vi) the design of policies to alleviate inter-ethnic tensions in Sub-Saharan Africa.

    Key words

    Political Economy, Media Economics, Identity Politics

    ORCID

    : 0000-0003-2833-0063