MULTI-COLOR IMAGING

Melike Lakadamyali, Maria Garcia-Parajo; Pablo Gomez
FUNDACIO INSTITUTDE CIENCIES FOTONIQUES, Barcelona (ES)

The disclosure relates to a method and an imaging device for multi-color imaging using frequency-modulated illumination. The method comprises a step of providing electromagnetic radiation with a plurality of different wavelengths, comprising a step of modulating each wavelength with a different modulation frequency, a step of illuminating a target with the modulated electromagnetic radiation, in particular for excitation of a target, a step of sensing electromagnetic radiation emitted from the target, in particular the luminescence, more in particular the fluorescence, and a step of processing the data obtained in the step of sensing

Filing date: 28 May, 2020

Licenced date: 29 Mar, 2022

US11,287,628B2

CD22 Targeting-moiety for the treatment of B-cell acute lymphoblastic Leukemia (B-ALL).

MENÉNDEZ BUJÁN, Mr. Pablo; VELASCO HERNÁNDEZ, Ms. Talía; ROMINA ZANETTI, Ms. Samanta; ENGEL ROCAMORA, Mr. Pablo; SÁNCHEZ MARTÍNEZ, Mr. Diego; GUTIERREZ AGÜERA, Mr. Francisco
IJC

The present invention provides therapeutics for the treatment of CD22-positive cancers such as B-cell acute lymphoblastic eukemia (B-ALL). In particular, the present invention provides an anti-CD22 monoclonal antibody whose F(AB')2, particularly the scFv fragment, can target the CD22 antigen, for use in the treatment of CD22-positive cancers.

Filing date: 11 Mar, 2020

Licenced date: 16 Jul, 2020

EP20382175.6

Method to photo-capture CO2 with perovskite oxide compounds

Pérez Tomás, Mr. Amador; Rubio Lorente, Mr. Carles; Sauthier, Mr. Guillaume; David, Mr. Jeremy; Vales Castro, Mr. Pablo; Arbiol Cobos, Mr. Jordi; Santiso López, Mr. Jose; Catalan Bernabé, Mr. Gustau
ICN2

The present application refers to a method for CO2 capture wherein light, particularly ultraviolet illumination, greatly improves the amount of CO2 captured on engineered perovskite oxide compounds. By a photorefractive phenomenon under near ultraviolet illumination, ionized defects are created at the surface of B-site defective oxide perovskites which act as additional CO2 trapping centres. The present method can be implemented at a temperature between -10ºC and 80ºC, and is cyclable, i.e. the perovskite oxide compounds can be regenerated by heat and used for subsequent CO2 capture.

Filing date: 30 Dec, 2019

PCT/EP2020/088044

Gene editing based cancer treatment

Raul Torres, Pablo Menendez, Sandra Rodriguez-Perales

Filing date: 14 Oct, 2019

PCT/EP2019/078408