The ICREAs

ICREA Research Professors form a vibrant community of scientists and researchers in all areas of knowledge that contribute to the advancement of humankind by exploring, interpreting and questioning. Have a look and learn about their amazing discoveries and findings here:

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    Alejandro Goñi
    Goñi, Alejandro R.
    Research Professor at
    Institut de Ciència de Materials de Barcelona (CSIC - ICMAB)
    Engineering Sciences
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    Research interests

    I am an experimental physicist with broad interests and experience in solid-state physics, optical spectroscopy (Raman scattering, photoluminescence, etc.), nanoscience and technology, energy materials, physics of low-dimensional materials (superlattices, quantum wires and dots), highly correlated electron systems, and high-pressure techniques. Essentially, I use light as a probe of the physical properties of all kinds of molecular materials and organic and/or inorganic nanomaterials, looking for new behaviors or phenomena that arise as a direct consequence of the reduced dimensionality and/or size of the material system under study. Although I dedicate myself to basic research, I always have a clear application in mind, such as improving the performance of optoelectronic devices, enhancing thermoelectric and/or photovoltaic properties, boosting solar energy conversion efficiency, develop ultra-sensitive spectroscopic techniques, etc. I currently lead group activities on high pressure physics, hybrid metal-halide perovskites, plasmon-assisted hot-electron emitters and the development of a spectrum-on-demand light source.

    Key words

    solid-state physics, optical spectroscopy, nanosciences & nanotechnology, high-pressure physics

    ORCID

    : 0000-0002-1193-3063

    RESEARCHER ID

    : M-2239-2014
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    Miguel Ángel González Ballester
    González Ballester, Miguel A.
    Research Professor at
    Universitat Pompeu Fabra (UPF)
    Engineering Sciences
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    Research interests

    My research focus is on computerised medical image analysis and computer-assisted surgery, including: image processing and computer vision, image-based diagnosis through machine learning, deep learning, medical imaging physics, computational modelling and simulation of virtual organs and surgical interventions, navigation in computer-assisted surgery, surgical devices and implants, and applied clinical research. In addition to basic research with solid mathematical foundations (notably my work on statistical biomechanical models), all my projects have a marked translational character, focusing on concrete clinical and industrial applications.

    Key words

    Medical imaging, computer vision, computer-assisted surgery, biomechanics, technology transfer

    ORCID

    : 0000-0002-9227-6826
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    González García, Maria Concepción
    Research Professor at
    Universitat de Barcelona (UB)
    Experimental Sciences & Mathematics
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    Research interests

    I am a theoretical particle physicist. I study the fundamental laws that govern the behaviour of the smallest components of Nature: the elementary particles. I do it by comparing the predictions from different theories with measurements performed at accelerators, where high energy beams of matter are made to collide, as well as in experiments which detect the elementary particles arriving to us from outer space, and which were produced in the burning of the stars or during the reactions occurring in the early Universe. The ultimate goal is two-fold: understand the physical laws of the microcosms as well as how they determine the Universe we live in.

    Key words

    Theoretical Particle Physics, Astroparticle Physics
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    Cayetano González
    González Hernández, Cayetano
    Research Professor at
    Institut de Recerca Biomèdica (IRB Barcelona)
    Life & Medical Sciences
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    Research interests

    We use Drosophila to investigate the molecular and cell biological mechanisms that drive cell proliferation and malignant growth. 
    Ongoing research lines include the following. 

    (1) Drosophila models of paediatric cancer. 

    (2) The molecular basis of sex-linked differences in cancer.

    (3)The role of cancer-testis (a.k.a. cancer-germline) genes in somatic malignant growth.

    Key words

    Cell Division, Drosophila melanogaster, Centrosomes, Stem Cells, Ewing sarcoma, Cancer.

    ORCID

    : 0000-0002-5259-3608
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    Pau Gorostiza
    Gorostiza Langa, Pau
    Research Professor at
    Institut de Bioenginyeria de Catalunya (IBEC)
    Life & Medical Sciences
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    Research interests

    Research in the laboratory focuses on developing nanoscale tools to study biological systems. These tools include instrumentation based on proximity probes, such as electrochemical tunnelling microscopy and spectroscopy, that we apply to investigate electron transfer in individual redox proteins, and other biophysical and biochemical interactions. These studies are relevant to the development of biosensors and molecular electronics devices, and have led to the discovery of long-distance electrochemically gated electron transport between partner proteins of the respiratory and photosynthetic chains. Another set of nanotools that we are developing is based on engineered molecular actuators that can be switched with light, such as azobenzene, which can be chemically attached to biomolecules in order to remotely control their activity (photopharmacology). They include peptide inhibitors of protein-protein interactions, small molecule enzymatic inhibitors, and photoswitchable ligands of a diversity of other proteins. Among several applications, these compounds have enabled photoactivated chemotherapy, photocontrol of cellular signaling mediated by ion channels and G protein-coupled receptors, photocontrol of cardiac activity and locomotion, pupillary reflex, sensory restoration, and photocontrol of brain waves. Based on these tools, we have also developed two-photon pharmacology to manipulate and study the activity of neurons and glia in intact brain tissue with pharmacological selectivity and sub-cellular three-dimensional resolution.

    Key words

    electrochemistry, scanning tunneling microscopy and spectroscopy, redox proteins, electrophysiology, neurobiology, neuroscience, photoswitch, photopharmacology, optopharmacology, optogenetics, biophysics, bioengineering, phototherapy, two photon

    ORCID

    : 0000-0002-7268-5577

    RESEARCHER ID

    : Q-2544-2015
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    Mariona Graupera
    Graupera Garcia-Mila, Mariona
    Research Professor at
    Institut de Recerca contra la Leucèmia Josep Carreras (IJC)
    Life & Medical Sciences
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    Research interests

    The Graupera lab studies how signaling events regulate vessel morphogenesis, and how this knowledge can be translated into therapeutic opportunities for diseases characterized by aberrant vessel growth. Current topics of interest are (i) How the endothelium instructs organ function in an organotypic fashion, (ii) How mural cell plasticity can be targeted to prevent disease pathogenesis and progression, and (iii) Why there is distinct endothelial spatio-temporal sensitivity to oncogenic mutations. Her research combines zebrafish and mouse models, patient derived samples, high-throughput analysis (NGS, single cell RNA sequencing, (phospho)proteomics) and high-resolution imaging. 

    Key words

    Endothelial cells, vascular biology, PIK3CA, PI3K

    ORCID

    : 0000-0003-4608-4185