Destacados

Cada año, un comité de expertos debe acometer una ardua tarea: de entre todas las publicaciones de ICREA, debe escoger unas cuantas que destaquen del resto. Es todo un reto: a veces los debates se acaloran, y siempre son difíciles, pero acaba saliendo una lista con las mejors publicaciones del año. No se concede ningún premio, y el único reconocimiento adicional es el honor de ser resaltado en la web de ICREA. Cada publicación tiene algo especial, ya sea una solución especialmente elegante, un éxito espectacular en los medios de comunicación o la simple fascinación por una idea del todo nueva. Independientemente de la razón, se trata de los mejores de los mejores y, como tales, nos complace compartirlos aquí.

LIST OF SCIENTIFIC HIGHLIGHTS

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  • 400,000 year-old fossil cranium from Gruta da Aroeira, Almonda karst system (Portugal) (2017)

    Zilhão, João (UB)

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    400,000 year-old fossil cranium from Gruta da Aroeira, Almonda karst system (Portugal)

    The fossil  is the westernmost Middle Pleistocene cranium of Europe and is one of the earliest fossils from this region associated with Acheulean tools. Unlike most other Middle Pleistocene finds, which are of uncertain chronology, the Aroeira 3 cranium is firmly dated to around 400 ka and was in direct association with abundant faunal remains and stone tools. In addition, the presence of burnt bones suggests a
    controlled use of fire. The Aroeira cranium represents a substantial contribution to the debate on the origin of the Neandertals and the pattern of human evolution in the Middle Pleistocene of Europe.

  • Certified randomness in quantum physics (2016)

    Acín Dal Maschio, Antonio (ICFO)

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    Certified randomness in quantum physics

    Randomness is a fascinating concept that attracts the interest of multiple thinkers, from philosophers, to mathematicians, physicists, computer scientists and engineers. From a fundamental perspective, the question of whether random processes exist is essential for our understanding of nature. From an applied perspective, randomness is a valuable resource for cryptography, algorithms and simulations. Standard methods for generating randomness, including the current quantum solutions, rely on strong assumptions on the devices that are difficult to meet in practice. However, quantum correlations violating a Bell inequality allow for completely new methods for generating certified randomness. These methods are known as device-independent because they don't require any modelling of the inner working of the devices. Moreover, they are intrinsically quantum, as no classical system can violate a Bell inequality. Device-independent quantum random-number generators protocols represent a change of paradigm for randomness that solve fundamental and practical drawbacks of standard schemes. The article reviews the efforts and the theoretical and experimental challenges to design device-independent randomness generation protocols. Generators with unprecedented standards of quality and security seem within reach using quantum technologies.

  • A “Molecular Selfie” reveals how a chemical bond breaks: Proton is seen escaping the molecule (2016)

    Biegert, Jens (ICFO)

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    A “Molecular Selfie” reveals how a chemical bond breaks: Proton is seen escaping the molecule

    Imagine what it would be like to watch how the individual atoms of molecules rearrange during a chemical reaction to form a new substance, or to see the compounds of DNA move, rearrange and replicate. The simple idea of watching how molecules break, or transform, during chemical reactions has, until now, been unfathomable since it requires tracking all of the atoms, which constitute a molecule, with sub-atomic spatial and few-femtosecond temporal resolution. Hence, taking such “snapshots” with a combined spatio-temporal resolution to witness a molecular reaction was considered fodder for science fiction.

    In their recent study, reported in Science, the team led by ICREA Prof. Dr. Jens Biegert head of the Attoscience and Ultrafast Optics Group at ICFO in collaboration with researchers from the USA, the Netherlands, Denmark and Germany, have reported the first real time and space imaging of molecular bond breakup in acetylene (C2H2) nine femtoseconds (1 femtosecond = 1 millionth of a billionth of a second) after its ionization. The team was able to track the individual atoms of one isolated acetylene molecule with a spatial resolution as small as 0.05 Ångström – less than the width of an individual atom – and with a temporal resolution of 0.6 femtoseconds. What’s more, they were able to trigger the breakup of only one of the bonds of the molecule and see how one proton leaves the molecule.

    The team took a single electron, steered it along a specific path with the laser and scattered it off an isolated molecule to record its diffraction pattern. It is mind-boggling to imagine the length and time scales of the experiment. The fantastic cooperation between experimentalists and theorists, atomic physicists and quantum chemists from ICFO, Kansas State University, Max-Planck-Institut für Kernphysik, Physikalisch Technische Bundesanstalt, Center for Free Electron Laser Science/DESY/CUI, Aarhus University, Friedrich-Schiller University Jena, Leiden University, and Universität Kassel made it possible to achieve such feat.

  • Saving freshwater from salts: Global call to change the way we regulate salinity (2016)

    Brucet, Sandra (UVIC)

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    Saving freshwater from salts: Global call to change the way we regulate salinity

    Many human activities such as agriculture and mining are increasing water salinity in rivers and lakes and this has adverse effects on human health and ecosystem functioning. It can also have high economic costs due to loss of ecosystem services and direct costs related to water for human consumption. Our study also warns that in most cases preventive actions focus solely on human uses of water, ignoring the protection of aquatic biodiversity. Some countries have made progress in regulating salinity on the basis of ecological criteria. Even so, the degree of protection is insufficient. In most cases these are only recommendations based on the total quantity of salt, without taking into account the concentration of different ions that have different toxicity.

    We call for global solutions and preventive policies based on the scientific consensus, taking into account social, economic and environmental issues in order to protect aquatic ecosystems from increasing salinity. We also predict that climate change will aggravate this situation because water evaporation will increase, diminishing the capacity of rivers and lakes to dilute salts, and sea level rise will cause intrusion in coastal freshwaters. We propose incentives for good practices and the use of technology that will reduce salt concentrations in freshwaters. We also recommend permits and controls for enterprises that discharge salt-rich effluents into freshwaters in order to control the concentration and timing depending on the dilution capacity of receiving waters.

    Ecological disasters caused by increasing salinity, though few in number, have brought about large-scale loss of biodiversity and suffering for human inhabitants affected, as is the case of the fisheries collapse in the Aral Sea. We are still in time to prevent further disasters if appropriate prevention practices are put in place. Nonetheless, increasingly saline aquifers and arable land already make it impossible to cultivate certain crops (e.g. Ebro valley), rendering it harder to provide drinking water. The countries of southern Europe will suffer most from this situation and experience greatest difficulties in economic activities.

     

  • A big year for a small effect   (2016)

    Catalán Bernabé, Gustau (ICN2)

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    A big year for a small effect  

    Flexoelectricity is a property of all insulating materials whereby they generate a voltage when they are bent. Flexoelectricity is however a tiny, almost inmeasurable, effect at the macroscale, hence it remains relatively unknown. This year, however, there have been a couple of notable advances may change the status of flexoelectricity. The first has been the demonstration that, at the nanoscale, electromechanical actuators can be made that bend in response to voltage1. The key to their big performance is that things are much easier to bend when they are nanoscopically thin. In addition to being competitive in terms of performance, flexoelectric actuators also have other advantages over competing piezoelectric technology: their architecture is simpler, their performance is more linear and less temperature-dependent, and the range of available flexoelectric materials is enormous. Last, but not least, our flexoelectric actuators are made on silicon substrates, meaning that they are compatible with the key material and fabrication processes already used by microelectronics industry, which should facilitate their industrial uptake.

    In parallel with the effort to make devices that exploit the large magnitude of flexoelectricity at the nanoscale, there is also a very active search for ways to make it meaningful also at the macroscale. Here we have made a major breakthrough discovery: by bending semiconductors it is possible to achieve effective flexoelectric coefficients that are hundreds and even thousands of times larger than for insulators2. An important additional aspect of semiconductor flexoelectricity is that it grows with thickness. This means that, unlike insulators, semiconductor flexoelectrics remain as potent at the macroscale as they are at the nanoscale. 

  • Cell therapy to regenerate retina (2016)

    Cosma, Maria Pia (CRG)

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    Cell therapy to regenerate retina

    Retinitis pigmentosa affects 1 in 3,500 individuals, who undergo progressive loss of vision, and for which currently there is no cure. Our approach aims to regenerate the photoreceptors, specific cell type in the retina, which respond to light. 

    We transplanted adult stem cells isolated from the bone marrow of mice and we observed fusion of these cells with Müller glia, a type of retinal glial cells which has a variety of functions. The Wnt signaling pathway is activated in the bone marrow cells before they are transplanted. We observed enhanced survival and proliferation of the hybrids as well as their reprogramming into intermediate photoreceptor precursors, which finally differentiate into photoreceptors. We demonstrated that this type of cell transplantation can rescue the retinal degeneration phenotype in retinitis pigmentosa mice.

    Although the mammalian nervous system is unable to replace neuron lost due to degeneration, our findings suggest that photoreceptors can be generated by the reprogramming of Müller glia. In the future, this approach may have the potential to be used as a strategy for reversing retinal degeneration and cure blindness.