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Brander, Christian

ICREA Research Professor at Institut de Recerca de la Sida - IrsiCaixa (IrsiCaixa).
Life & Medical Sciences

Short biography

Christian Brander obtained his PhD in Immunology from the University of Bern and completed his post-doctoral training at Harvard Medical School focusing on T cell immunity to HIV. He joined ICREA in 2008 with an appointment at the IrsiCaixa AIDS Research Institute. He is a co-inventor of the HIV "HTI" immunogen, which is developed clinically by Aelix Therapeutics Inc. where he is a co-founder and CSO. He serves as a curator of the Los Alamos HIV Database and is an Associate Professor at the University of Vic.

Research interests

Our group aims to understand the cellular immunity to viral infections. Using complementary sets of immune analyses and integrated -omics approaches, we seek to identify functional correlates of virus control and to explore their underlying cellular and molecular mechanisms. We combine cellular assays and methylome, communicome and transcriptomics analyses to assess to what degree and at what stages of different viral infections the effector function profiles of virus-specific T cells are epigenetically controlled. We also pay special attention to the effect of viral infections on neurological function.

Key words

HIV, cellular immunity, host genetics, viral evolution, viral immunity in solid organ transplantation, neuro HIV

ORCID

0000-0002-0548-5778
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