Els ICREA

Els professors d'investigació ICREA formen una comunitat dinàmica de científics i investigadors de totes les àrees del coneixement, que contribueixen al progrés de la humanitat amb els seus estudis, interpretacions i preguntes. Entreu i descobriu-ne els increïbles descobriments i troballes:

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    Arribas López, Joaquín Vicente
    Research Professor at
    Parc de Salut Mar (PSMAR)
    Life & Medical Sciences
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    Research interests

    • Development of novel therapeutic strategies to treat HER2-positive tumors and identify mechanisms of resistance to current therapies.
    • Development and preclinical characterization of T cell-based therapies against HER2 positive tumors.
    • Characterization of the role of premature senescence in breast cancer progression and treatment.
    • Evaluation of the activity of novel anti-cancer therapies in breast and pancreatic cancer patient-derived xenografts.

    Key words

    breast cancer, HER2, immunotherapy, metalloproteases, senescence, metastasis
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    Aznar Benitah, Salvador
    Research Professor at
    Institut de Recerca Biomèdica (IRB Barcelona)
    Life & Medical Sciences
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    Research interests

    Our global aim is to characterize the molecular pathways that regulate the behaviour of normal stem cells during homeostasis, and how they become deregulated during carcinogenesis and ageing. Research Lines: - What intrinsic mechanisms regulate adult stem cell function, and how are they deregulated during ageing and cancer? - How do adult stem cells communicate with their local environment and how is the system coordinated to dictate stem cell function? - What systemic cues communicate with adult stem cells and how do distant adult stem cells coordinate their function at the level of the whole organism? - How does deregulation of pathways that control stem cell behaviour contribute to the maintenance and progression of carcinomas?

    Key words

    Adult Stem cells, tissue homeostasis, cancer
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    Bagaria i Pigrau, Joan
    Research Professor at
    Universitat de Barcelona (UB)
    Experimental Sciences & Mathematics
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    Research interests

    I am a mathematical logician working mainly in Set Theory, an extremely general theory whose objects of study are the abstract infinite sets. Set Theory is the strongest and most encompassing of mathematical theories. It is both the theory of infinity and the standard foundation for mathematics, in the sense that virtually all of mathematics can be formally reduced to it. I help to develop and apply sophisticated techniques, such as Forcing and Large Cardinals, towards the solution of hard problems in Set Theory itself and in other areas of logic and mathematics. More interestingly, it is sometimes possible to prove that a given problem cannot be solved using standard mathematical tools, which are embodied in the standard Zermelo-Fraenkel with Choice (ZFC) axioms of Set Theory, and therefore new axioms are needed for its solution. Finding and classifying new axioms, thereby expanding the frontiers of mathematical reasoning, is also an essential part of set theory, and of my work.

    Key words

    Set theory, logic, foundations and philosophy of mathematics.

    ORCID

    : 0000-0002-4686-8222

    RESEARCHER ID

    : L-5958-2014
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    Baizán Muñoz, Pau
    Research Professor at
    Universitat Pompeu Fabra (UPF)
    Social & Behavioural Sciences
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    Research interests

    My research focuses in two main areas: a) the study of the trends and patterns of family formation dynamics and, b) the changing patterns and determinants of migration. I explore several theoretical perspectives to explain the observed behaviour and apply quantitative techniques to disentangle the relationships between processes. For instance, I investigate questions such as "To what extent do employment insecurity and de-standarisation of work patterns affect the likelihood to enter a partnership and to have a child?", "How does this impact vary across countries, regions and different welfare state regimes?", "What is the impact of changing gender roles on fertility behaviour?", "What are the causes of African migration?", "How migration influences family behaviour?".

    Key words

    fertility, migration, family formation, social policies, event history analysis

    ORCID

    : 0000-0003-0117-8794

    RESEARCHER ID

    : B-7571-2014
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    Ballester Balaguer, Pablo
    Research Professor at
    Institut Català d'Investigació Química (ICIQ)
    Experimental Sciences & Mathematics
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    Research interests

    My scientific background lies in the areas of organic chemistry (making molecules) and supramolecular chemistry (study how molecules fit together). My research is mainly focused in the design, synthesis, study and characterization of functional molecular aggregates. I consider myself a mixture between a molecular architect and a molecular engineer. We study matter but we also produce matter and new materials. We work in trying to understand molecular self-assembly processes (non-covalnet synthesis) as a methodology to construct large and functional supramolecular assemblies, i.e., molecular machines. A second area of interest resides in the design and application of molecular containers. These are molecular or supramolecular structures with an internal cavity sufficiently large to include or encapsulate other molecules. Unfortunately, although we construct monumental and even artistic structures they are not visible to the naked eye due to their reduced nanometer size.

    Key words

    Supramolecular Chemistry, Molecular Recognition, Physical Organic Chemistry

    ORCID

    : 0000-0001-8377-6610

    RESEARCHER ID

    : B-6436-2011
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    Baroni, Marco
    Research Professor at
    Universitat Pompeu Fabra (UPF)
    Social & Behavioural Sciences
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    Research interests

    Marco is interested in human language and how it is acquired. To gain insights into these questions, he develops and studies computational systems, in particular deep neural networks, that acquire aspects of language from realistic input data. By analyzing the inner dynamics and external behaviour of these systems, we can gain insights into questions such as: how much linguistic knowledge is already implicitly present in input distributions, what are the minimal priors necessary for learning, what is the space of solutions to the communication challenges that led to the evolution of language, and so on. The ultimate goal of Marco's research is to bring about a more precise characterization of what is unique about the human language faculty.

    Key words

    linguistics, cognitive science, natural language semantics, grammar, computational simulations, distributed representations, neural networks, compositionality and generalization

    ORCID

    : https://orcid.org/0000-0001-5066-3580