Els ICREA

Els professors d'investigació ICREA formen una comunitat dinàmica de científics i investigadors de totes les àrees del coneixement, que contribueixen al progrés de la humanitat amb els seus estudis, interpretacions i preguntes. Entreu i descobriu-ne els increïbles descobriments i troballes:

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    Davide Debortoli
    Debortoli, Davide
    Research Professor at
    Universitat Pompeu Fabra (UPF)
    Social & Behavioural Sciences
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    Research interests

    Davide Debortoli main research interests are in the area of macroeconomics, with a special focus on business cycles, fiscal policies and monetary policies. One of his line of research has focused on the implications of (lack of) government credibility for the design of optimal fiscal and monetary policies, and for public debt management. In a different line of research he studies the role of heterogeneity and inequality among households for the propagation of aggregate shocks, and the associated policy implications.

     

     

     

    Key words

    Macroeconomics, Fiscal Policy, Monetary Policy

    ORCID

    : 0000-0001-8012-1790

    RESEARCHER ID

    : K-5785-2014
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    Gustavo Deco
    Deco, Gustavo
    Research Professor at
    Universitat Pompeu Fabra (UPF)
    Engineering Sciences
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    Research interests

    Perceptions, memories, emotions, and everything that makes us human, demand the flexible integration of information represented and computed in a distributed manner. Normal brain functions require the integration of functionally specialized but widely distributed brain areas. The main aim of my research is to elucidate precisely the computational principles underlying higher brain functions and their breakdown in brain diseases. My research allows us to comprehend the mechanisms underlying brain functions by complementing structural and activation based analyses with dynamics. We integrate different levels of experimental investigation in cognitive neuroscience (from the operation of single neurons and neuroanatomy, neurophysiology, neuroimaging and neuropsychology to behaviour) via a unifying theoretical framework that captures the neural dynamics inherent in the computation of cognitive processes.

    Key words

    Computational, Cognitive and System Neurosciences
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    Dan Dediu
    Dediu, Dan
    Research Professor at
    Universitat de Barcelona (UB)
    Humanities
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    Research interests

    My research is quite diverse, including the processes that shape linguistic diversity, the origins and evolution of language in the context of human evolution, and the application of quantitative and computational methods to the language sciences. In particular, I have been focusing on studying the influence of non-linguistic factors on linguistic diversity, such as the effect of vocal tract anatomy on phonetics and phonology, the effect of the bio-physical environment on language spread and on the color vocabulary, and of population genetics on linguistic tone, using statistics and computer modelling. I have been arguing that language and speech are an old feature of our evolutionary lineage, being shared, in some form, with our cousins, the Neanderthals and the Denisovans.

    Key words

    linguistic diversity; language evolution; genetic foundations of language; phonetics; statistics; computer modelling

    ORCID

    : 0000-0002-0704-6365

    RESEARCHER ID

    : E-3279-2012
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    Hernando del Portillo
    del Portillo Obando, Hernando A.
    Research Professor at
    Institut de Salut Global Barcelona (ISGlobal)
    Life & Medical Sciences
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    Research interests

    My main research area is the biology of Plasmodium vivax, a neglected human malaria parasite responsible for millions of yearly clinical cases. We are presently looking for mechanistic insights of the role of reticulocyte-derived exosomes, nanovesicles of endocytic origin, in signalling the spleen and the bone marrow to estabish cryptic erythrocytic infections.  To pursue bone marrow and spleen studies,  we are implementing the usage of humanized mouse models and organs-on-chip. To use this information in novel control strategies, we are exploring the use of reticulocyte-derived exosomes as a novel vaccine against P. vivax as well as novel biomarkers of asymptomatic infections. Last, to rapidly move this field to translation, we are pursuing the development of exosome-based vaccines against infectious diseases of veterinary importance.

    Key words

    Malaria, Plasmodium vivax, exosomes, vaccine development, biomarkers, molecular insights pathology, lab chip

    ORCID

    : 0000-0002-5278-3452
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    Luciano Di Croce
    Di Croce, Luciano
    Research Professor at
    Centre de Regulació Genòmica (CRG)
    Life & Medical Sciences
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    Research interests

    Epigenetic changes, such as histone modifications and DNA methylation, are common alterations in cancer cells. Our laboratory is addressing the molecular basis of epigenetic alterations during the early phase of the tumorigenesis process. The expression of onco-proteins in hematopoietic precursor cells provides a unique model system to follow the molecular step from a normal to a transformed cell on the level of gene transcription, nuclear structure and chromatin. More recently, Di Croce lab is interested in understanding how variations in the assembly of the Polycomb complexes occur and influence mES cell differentiation and animal development, and th erole of 'oncohistone' in pediatric cancers.

    Key words

    Cancer, Epigenetics, Gene regulation

    ORCID

    : http://orcid.org/0000-0003-3488-6228

    RESEARCHER ID

    : E-7759-2015
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    Margarita Díaz Andreu
    Díaz-Andreu García, A. Margarita
    Research Professor at
    Universitat de Barcelona (UB)
    Humanities
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    Research interests

    The three main research areas in which Díaz-Andreu has been active and has led research groups in the last few years are still in place. Her work in rock art and archaeoacoustics is highly innovative and she leads an ERC interdisciplinary group of archaeologists, acoustic engineers, ethnomusicologists and psychologists. For this project, in 2022 fieldwork was undertaken in South Africa. She also published on the archaeoacoustics of Russian Altai. In the history of archaeology the highlight has been the publication of a book about the history of women in archaeology (518pp) and the running of the ArqueólogAs project, with the publication of 150+ biographies of women pioneers on the project’s webpage. Her work in the international DeepCities project has resulted in a publication about heritage values in urban transformation. She is leading investigator in all her three research groups of academics and students (ArqueólogAs, Artsoundscapes and GAPP/Deep Cities).

    Key words

    History of Archaeology, Prehistoric Art, Rock Art, Prehistory, Identity, Archaeoacoustics, Archaeological Heritage

    ORCID

    : 0000-0003-1043-2336

    RESEARCHER ID

    : B-6146-2014