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Melchiorre, Paolo
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ICREA Research Professor at ICIQ (Institut Català d'Investigació Química). Experimental Sciences & Mathematics
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Paolo Melchiorre is ICREA Research Professor at the Institute of Chemical Research of Catalonia (ICIQ), in Tarragona.
Paolo, born in 1973 in Camerino - Italy, studied Chemistry at the University of Bologna where he graduated in 1999. Then he began his doctoral studies in Chemistry working in the area of asymmetric catalysis. Before obtaining his PhD degree in 2003, he spent 10 months in Denmark working with Prof. Karl Anker Jørgensen at the “Center for Catalysis”, Århus University, where his studies centered on asymmetric organocatalysis. Afterwards, he worked as a postdoctoral associate at the Industrial Chemistry Faculty of the Bologna University. There he began his studies on the development of novel organocatalytic asymmetric transformations. In October 2007 he took a permanent position as an Assistant Professor at Bologna University. In September 2009 Paolo, together with his wife Lorna and their two kids, moved to Catalonia as ICREA Professor and ICIQ Group Leader.
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Research Interests
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Catalysis with small organic molecules (Asymmetric Organocatalysis), where an inorganic element is not part of the active principle, has become a highly dynamic area in chemical research. In the decade, this field has grown at such an extraordinary pace that it is now recognized as an independent area of synthetic chemistry.
Our research aims to exploit the potential of Asymmetric Organocatalysis, where an inorganic element is not part of the active principle, to find cost-effective, environmentally benign, and sustainable synthetic methods to assemble a library comprising enantiopure, complex, chiral molecules embodying features of natural products that increase the probability of success in the identification of drug-candidate structures. The main emphasis is on discovery of new catalytic cascade reactions, and efficient assemble of diverse and medicinally important chemical structures.
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KeyWords
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Asymmetric Synthesis, Catalysis, Chemical Biology, Organocatalysis
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