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Chillón Rodríguez, Miguel
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ICREA Research Professor at UAB (Universitat Autònoma de Barcelona). Life & Medical Sciences
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Born in Barcelona in 1966. PhD in Genetics, on Cystic Fibrosis Mutations in humans, Hospital Duran i Reynalds and University of Barcelona, 1994. National Award in Human Genetics by the Spanish Association of Human Genetics in 1995. HHMI postdoctoral fellow on Gene Therapy for Cystic Fibrosis, at the Internal Medicine Dept, University of Iowa, USA (1994-1997). EMBO fellow in Genethon III (Evry, France) (1997-1999) on Development of viral vectors for Gene Therapy. Postdoctoral fellow in the Veterinary School of the Universitat Autonoma de Barcelona (UAB) on Gene Therapy for Type I Diabetes (2000-2001). ICREA Research Professor at the UAB since 2001. Scientific Responsible of the Vector Production Unit, a technological platform to produce Viral Vectors, since 2004. Assistant Professor of the Biochemistry and Molecular Biology Dept at the UAB since 2005. Member of the Biosafety Committee of the UAB since 2006. He has published almost 50 papers on Human Genetics and Gene Therapy.
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Research Interest
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Medicine still has many challenges to solve specially on complex diseases were a large number of both, genetic and environmental factors are involved. Among them, autoimmune disorders have attracted attention because there are no effective curative treatments for them. Some of these autoimmune diseases affect the central nervous system, which in addition, is difficult to access and to manipulate with classical pharmacological treatments.
To address these problems we have focused our research interests in three main objectives: (1) gene therapy strategies for autoimmune diseases; (2) gene therapy strategies for diseases affecting the nervous system, such as neuromuscular and neurodegenerative disorders, and (3) development of more efficient and less immunogenic viral vectors.
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KeyWords
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Gene therapy, viral vectors, Crohn disease, helper-dependent adenovirus, chimeric adenovirus, autoimmune diseases; neurodegenerative diseases
mechanisms of memory formation
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