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Ribas de Pouplana, Lluís
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ICREA Research Professor at IRB (Institut de Recerca Biomèdica de Barcelona). Life & Medical Sciences
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Born in Girona. He studied Biology at the University of Barcelona, and Biochemistry at Edinburgh University, where he obtained a PhD in 1992 with the help of a fellowship from La Caixa/British Council.
He then joined the Biology department of the Massachusetts Institute of Technology as a postdoc. In 1997 he moved to The Scripps Research Institute where he became assistant professor of Molecular Biology in 2001.
In 2003 he joined ICREA, and became Principal Investigator at the Institute for Research in Biomedicine, where he heads the Laboratory of Gene Translation.
He is the founder of two biotechnology companies and currently serves as Chief Scientific Officer of Omnia Molecular SL. Omnia Molecular is an antiinfectives discovery company, with twelve employees currently located at the Barcelona Science Park.
In addition, Dr. Ribas serves in the Scientific Advisory Board of aTyr Ltd, and is a patron of the FCRI, the Catalan Foundation for Research and Innovation.
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Research Interests
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Our laboratory investigates the process of protein synthesis. In particular, we focus on aspects of tRNA biology that cause human disease when affected by mutation or misregulation.
Currently we are focused on two topics:
- The study of human diseases caused by mitochondrial tRNA mutations, and in the analysis of the role of tRNA chemical modifications in the control of gene expression.
- The study of the role of chemical modifications in tRNAs in the regulation of protein synthesis in humans.
We remain interested in the transference of the scientific knowledge that we generate to biomedical applications. Although it is impossible to know in advance what new solutions may come out of any given research project, we strive to turn our scientific results into practical solutions to relevant medical problems.
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Key Words
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protein synthesis
origin of life
metabolic diseases
biotechnology
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